The Wright Center: Hepatitis C, A Dangerous but Highly Treatable Disease Members News July 2, 2025 By Dr. Jignesh Y. Sheth I’m here today to talk about a disease of grave seriousness — hepatitis. In recent years, the medical community has made significant strides in combating this global scourge. Still, much work remains, so I’m happy there are awareness events like World Hepatitis Day, which is celebrated on July 28. The day brings attention to viral hepatitis, which each year claims more than a million lives. Put simply, hepatitis is an inflammation of the liver. There are five main types of hepatitis: A, B, C, D, and E. The one that gets the most attention is hepatitis C, an especially pernicious form of the disease that is contracted through the blood of an infected person. More than 4 million people in the U.S. have hepatitis C, with half of those cases undiagnosed. Hepatitis C can be contracted in several ways, including through sharing needles, equipment used for preparing or injecting drugs, sex, sharing personal items, or unregulated tattoos or piercings. A small percentage of infants are infected through their mothers. Most people with hepatitis C are saddled with a lifelong infection, which left untreated can cause severe health problems including chronic liver disease, liver failure, liver cancer and, in the worst cases, death. The trick is catching it in time, which can be difficult, since the disease tends to develop almost imperceptibly at first. When symptoms do take hold, they include jaundice, lack of appetite, vomiting, stomach pain, fever, dark urine, light-colored stool, joint pain, and fatigue. They usually appear within two to 12 weeks, but can take up to six months to develop. Given the severity of the disease, all adults ages 18 and older should be screened for hepatitis C at least once in their lives through a simple and easily available blood test. Among those at elevated risk who should be screened are baby boomers; people who had blood transfusions before 1992; people who have undergone long-term dialysis treatments; people who have used illicit drugs; people living with HIV; babies born to mothers diagnosed with hepatitis C; and sexual partners of anyone diagnosed with the disease. I want to emphasize that hepatitis C is a very treatable — even curable — disease, and I’m proud to say that we at The Wright Center are one of Northeast Pennsylvania’s leaders in treatment. People who test positive for the disease are treated with oral medications that help clear the virus from the bloodstream. About 90% of patients are cured after eight to 12 weeks of treatment, according to the Centers for Disease Control and Prevention. And there are many healthy habits patients can adopt to mitigate the disease’s progression, including reducing alcohol intake, maintaining a healthy weight, being careful with over-the-counter medications, and receiving regular medical care that includes monitoring for liver cancer. Besides incorporating testing, prevention, care, and treatment into our patient-centered medical home model approach, we also provide essential services like outreach, patient education, case management, and care coordination as a means of improving the health outcomes for patients living with the disease. Even if you don’t think you have hepatitis C, please make it a point to get tested sometime in the near future. Be proactive — it really can make all the difference. Jignesh Y. Sheth, M.D., FACP, MPH, is senior vice president and enterprise chief operations and strategy officer at the Wright Centers for Community Health and Graduate Medical Education. He is dually board-certified in internal medicine and addiction medicine.
